In this class, we will try to identify genomic islands (GI; DNA containing multiple genes that are often transferred between bacterial strains) and track down when and how these were transferred.
Before working on the project, students should take a tutorial class (available here) to familiarize themselves about bioinformatics of comparative genomics and how to use the EzBioCloud cloud platform.
We will use the same data set as “Vibrio cholerae tutorial set”. Please provide the answers to the following questions:
We will assume that dendrogram based on ANI (average nucleotide identity) reflects the real phylogeny.
Statistical comparison of genomic properties
In this analysis, the following genomic properties are compared to elucidate possible correlation between them. Genome size in Mbp (million base pairs) DNA GC content in