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Identification of Lachnospiraceae bacterium 5_1_63FAA

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The genome sequence that is labeled as “Lachnospiraceae bacterium 5_1_63FAA” has been included in most microbiome taxonomic profiling software tools, and has therefore appeared in many publications. The following list is a small sampling:

Since this genome is cited in many studies on the human gut microbiome, this species is likely to be a major component of us.

This genome was sequenced in 2011 and assigned as an unclassified species in the family Lachnospiraceae.

Lachnospiraceae bacterium 5_1_63FAA in NCBI

I used our TrueBac ID system with it’s up-to-date, taxonomically curated database to identify this genome sequence. The results show that this genome belongs to Anaerostipes hadrus. This species was first published as ‘Eubacterium hadrum’ in 1976, then reclassified in the genus Anaerostipes in 2013 (Allen-Vercoe et al. 2013).

TrueBac ID of Lachnospiraceae bacterium 5_1_63FAA

The ANI value is sufficiently higher than the proposed cutoff (95~96%) by Chun et al. (2018). Please also note that there are two other genomospecies closely related to 5_1_63FAA in this genus, namely, CYYH_s and MJIF_s.

I hope to see more of Anaerostipes hadrus 5_1_63FAA in the publications instead of Lachnospiraceae bacterium 5_1_63FAA in future.

by Jon Jongsik Chun

October 28, 2018

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