Powered by Precision, Driven by Quality

Pan-genome orthologous group (POG)

Subscribe To Our Newsletter

Get updates and learn from the best

Pan-genome orthologous group (POG) refers to “a group of orthologous genes (orthologs)” that are identified from multiple genomes. The below figure illustrates how POGs are identified.

In this example, a total of 10 POGs were identified from clustering 16 genes (CDSs) in 3 genomes.

  • Two POGs (#1 & 2) comprise the core-genome as they are present in all genomes.
  • Six POGs (#5~10) contain single CDS, called “singleton”.
  • Pan-genome of these 3 genomes consists of 10 POGs.

POGs are the basic unit of core- and pan-genome.

Last updated on May 10th, 2016 (EK)

Subscribe To Our Newsletter

Get updates and learn from the best

More To Explore

Identification of Ruminococcus sp. 5_1_39BFAA

Many genome sequences in public databases are used in metagenomic studies to understand the human microbiome. Unfortunately, many of the taxonomic identities of these genomes

천종식의 프로필

천종식 / Jon Jongsik Chun (주) 천랩 대표이사 / 서울대학교 생명과학부 교수 / 한국과학기술한림원 정회원 Google Scholar 페이지 마이크로바이옴에 대한 브런치(블로그) 한겨레신문 연재 <천종식의 미생물

Share This Post

Share on facebook
Share on linkedin
Share on twitter
Share on email
small_c_popup.png

Have a Question? Let's have a chat?

We're here to answer any question you might have

small_c_popup.png

Have a Question? Let's have a chat?

We're here to answer any question you might have

small_c_popup.png

Stay up to date

Keep up with our latest developments